NO GROW

Permanent Hair Remover In A Tube

 

 

 

 

HOW DOES NO GROW WORK?

NO Grow Hair Removal System is a topically applied hair removal cream with a difference. NO Grow is an easy to use wipe-on-wipe-off cream.

NO Grow Hair Removal System is a topically applied hair removal cream with a difference. NO Grow is an easy to use wipe-on-wipe-off cream.

Unlike most hair removal creams which focus on the temporary removal of surface hair, NO Grow is absorbed into the hair follicle and reacts with the matrix bulb of the hair root – the place where hair growth starts – to neutralise the hair root and stop hair growth permanently. The product must be applied on a weekly basis until the hair growth cycle has been completed (between 7 – 8 months depending on the individual consumer’s genetics).

NO Grow destroys the hair follicle, thus stopping the follicle from producing further hairs. It creates the same results as laser hair removal but by a completely different scientific route.

Each product in the NO Grow range is specifically formulated to target certain types of male and female facial and body hair and give you smooth, totally hairless skin.

NO GROW RECREATED THE CONDITIONS FOUND IN MALE PATTERN BALDNESS

Instead of damaging the hair root, like other hair removal systems, NO Grow gradually shrinks the root so it shrivels up and stops growing. The process is similar to male pattern baldness and leads to permanent hair loss. It is kind and gentle on the skin and reduces hair growth without damaging the surrounding tissue.

The nutrient engineering in NO Grow is carried out by a new breakthrough active compound Isoquinolinium Bromide – which safely recreates the conditions found in the matrix bulb of the hair root at the onset of male pattern baldness. Growth of new hair is reduced every time you use the cream.

After using and completing your hair growth cycle of about 7 – 8 months, you will have treated all hairs in the growth cycle and should notice a dramatic reduction in the density and thickness of hairs on your skin.

NO GROW WORKS IN CONJUNCTION WITH YOUR OWN HAIR GROWTH CYCLE

For NO Grow cream to have a permanent effect it needs to be applied once a week for a period of 7 to 8 months. With every successive application of the cream less and less hair will grow back. Each time you use NO Grow cream hair will become softer and less dense.

NO Grow Hair Removal Cream targets its action at the Anagen Phase (active growth stage) in the life cycle of body hair growth. It causes the debilitation of the follicle by starving the hair root of nutrients necessary to sustain hair growth.

THERE ARE THREE STAGES IN THE HAIR GROWTH CYCLE:

Anagen:  Active phase of hair growth

Catagen: The transitional phase

Telogen: The resting phase

 

Hair growth cycle

Treatment of the hair root with NO Grow can only take place during the Anagen phase. Therefore, hair that is in the Catagen or Telogen Phase will not respond to treatment.

That’s why NO Grow Hair Removal Cream must be applied at weekly intervals, once every week to ensure that all hair in all growth stages has been treated.

THE SCIENCE AROUND NO GROW

Growth Inhibitor ingredient, GSF2:0, bio-engineers the matrix bulb to neutralize hair roots to stop hair growing.

It has taken researchers, based in Japan three and a half years to develop the technology which enables NO Grow to modify the growing behaviour of hair roots, resulting, for the first time, in a long-term cessation (ending) of hair growth.

Cell division is responsible for the hair growth cycle. The new cells push the hair forward to make it grow longer, so the new hair is added at the root.

By bio-engineering the cells in the matrix bulb of the hair root to replicate the cell activity found at the onset of male pattern baldness, scientists have succeeded in halting hair growth.

By introducing new genetic instructions to the matrix, the follicle is programmed to eradicate (destroy) the hair root and stop further growth activity.

This discovery, together with the unique transdermal delivery technique (Nano-enhanced transportation technology), which enables NO Grow to be efficiently delivered to the hair root, is changing the beauty regime of millions of men and women.

NANO-ENHANCED TRANSPORTATION TECHNOLOGY

Technology used to manipulate the molecular structure of the active ingredients, breaking it down so fine that it is able to penetrate into the desired area for a period of 8 hours with the aid of TLR (time controlled release).

NO GROW MODIFIES THE MATRIX TO STOP HAIR GROWTH

The matrix bulb of the hair root us the place where hair growth starts and ends.These hair growth cells from the matrix bulb of hair root are seen as spheres of cultured papillae cells from human hair follicles. When GSF2:0 is introduced cell division is slowed down, shrinking and individually withering the root, until there is no more space for cell division i.e .no new hair folicle, similar to the effect of the onset of male pattern baldness.

NO Grow replicates the effects of laser hair removal but it achieves its goals by a very different scientific method.

For the first-time researchers have been able to take human dermal papilla cells from inside the base of human hair follicles and recreate cell structure found in patients with male pattern baldness. GSF2:0 replicates these cells which stifles new hair growth.

The breakthrough came with the development of GSF2:0 compound which modifies the growing behavior of hair roots, resulting, for the first time, in a long-term cessation of hair growth.

By bio-engineering the cells in the matrix bulb of the hair root to replicate the cell activity found at the onset of male pattern baldness, scientists have succeeded in restricting hair growth.

When introducing new genetic instructions to the matrix, the follicle is programmed to neutralize the hair root and stop further growth activity. This discovery, together with the unique transdermal delivery technique which enables NO Grow’s active ingredients to be efficiently delivered to the hair root, is changing the beauty regime of millions of men and women.

For the first time a product is available which modifies the growth activity of the hair root, but without damaging the skin or causing pain to the patient.

NO Grow was one of the first to develop ‘nutrient engineering’ techniques which restrict the flow of nutrients to the matrix hair bulb. This results in the miniaturisation of the hair root and ultimately restricts the growth of new hair.

NO GROW CLINICAL TRIALS

RESULTS OF CLINICAL TRIAL OF NO GROW HAIR REMOVAL CREAM

 METHOD

A total of 68 participants, 46 female and 22 males between the ages of 23 and 67 years, completed the trial. Six participants did not complete the trial for personal scheduling reasons. Participants were randomly split into two groups. Half were given NO Grow and half were given placebo consisting of moisturizing creams. This was applied at weekly intervals for four weeks on the same day over a trial period of 90 days.

RESULTS

Participants returned every week for measurement and evaluation. The following significant differences could be observed between NO Grow treated areas and the placebo treated areas of the skin. An overall decrease in hair density on areas with NO Grow of +/- 25% every week was measured using Cross-Section Trichometer over one scare centimetre of skin x 100 (mm2/cm2 x 100). Participants also noted a reduction in hair thickness during the trial.

CONCLUSION

At the conclusion of the 30 day study an overall decrease in hair density on NO Grow treated areas was +/- 93% measured using a Cross-Section Trichometer. NO Grow has been shown to be a safe and effective method for progressively reducing hair root growth.

CONDUCTED BE:

Dr Shibata, MD, Dr T. Saito, MD. J.L. Ueda.

Manila, Phillipines

24 February 2012

REFERENCES

  1. Jankovice SM, Jankovice SV. The control of hair growth. Dermatology Online Journal. 4(1):2, 1998.
  2. BernardBA.Haiiology:anupdate.IntJCosmetSci.24:13-16,2002.
  3. Stenn KS, Paul R. Controls of Hair Follicle Cycling. Physiol Rev. 81(1):449-494, 2001.
  4. Milner Y, Sudnik J, Filippi M, et al.Exogen, Shedding Phase of the Hiar Growth Cycle: CHaracterisation of a Human Model. J Invest Dermatol. 119:639-644. 2002.

5.Craven AJ, Ashby MG et al. Prolactin delays hair regrowth in humans. J Endocrinol. 191(2): 415-425, 2006.

6.Carbajo JM. Cosmetica Capilar. Dermafarmacia. Consejo General de Colegios oficiales de Farmaceutucos, Modulo 11. Madrid, 1989.

7.Mandt N, Troilius A, Drosner M. Epilation Today: Physiology of the Hair Follicle and Clinical Photo-Epilation. J Investig Dermatol Symo Proc. 10(3):271-274, 2005.

HOW DO THE ACTIVE INGREDIENTS WORK

To allow passage of the active ingredient Isoquinolinium Bromide to penetrate down to the matrix bulb of the hair root, NO Grow dissolves hair below the surface of the skin and “pulls” the active ingredients down the hair shaft to the hair matrix bulb – the place where hair growth starts – and in this case – stops. Because of its low molecular weight, it is able to penetrate deep inside the hair shaft.

Every time you use the cream less and less hair will grow back at the end of the cycle you should have achieved 99.5% hair reduction.

NO Grow needs to be applied every week for 7 – 8 months, for the cycle of hair growth to be fully covered. The cream reacts with the root when in the Anagen phase of the growth cycle. Cell division takes place during the growth cycle. The new cells propel the hair forward and make it grow longer; therefore the new hair is added at the root. By bio-engineering these cells, in the matrix bulb of the hair root, replicates the cell ac ty found at the onset of male pattern baldness. By introducing new genetic instructions to the matrix, the follicle is programmed to neutralize the hair root and stop further growth activity. This discovery, together with the unique transdermal delivery technique which enables NO Grow Hair Remover to be efficiently delivered to the hair root.

THE INGREDIENTS IN NO GROW.

THERE ARE NO ANIMAL OR HUMAN DERIVED INGREDIENTS IN NO GROWS

  • Products are 100% vegan and vegetarian. They do not contain any animal by-products or ingredients
  • Products are free from haram alcohols, animal derivatives, parabens and harmful chemicals
  • NO Grow ingredients have not been tested on animals and we are against all forms of animal testing

NO PARABENS

NO Grow products do not contain parabens or formaldehyde-releasing preservatives such as dialyzed urea. Parabens are a type of preservative used in many main-stream skincare and cosmetics. In recent years they have come under scrutiny as they’re believed to be ‘carcinogenic’ (an ingredient linked with causing cancer).

HALAL APPROVED INGREDIENTS

 NO Grow products are free from harsh haram alcohols such as ethanol and denatured alcohol and do not contain any animal derived ingredients.

RESPONSIBLE INGREDIENT SOURCING

NO Grow products are made with respect for Planet Earth. We source ingredients that are ethically harvested and that are sustainable. We always respect the ecosystem of local communities and help raise awareness about un-ethical ingredients found in cosmetic products.

NOT TESTED ON ANIMALS

 NO Grow ingredients have not been tested on animals and are free of all animal derived ingredients. Our company is strongly against all forms of animal testing and we insist on verifiable confirmation from our ingredient suppliers that this is the case.

 100% VEGAN & VEGETARIAN

NO Grow products are 100% Vegan & Vegetarian, i.e. they do not contain any animal ingredients at all such as part of an animal like gelatine or animal fats, or derived from an animal such as honey, beeswax, lactic acid, etc. Neither do they contain any animal bi-products.

NO SYNTHETIC COLOURING

We do not use any artificial colouring or dyes in any NO Grow products. F D & C colours are derived from coal tar and are a derivative of petroleum. They are known to cause cancer NO Grow products are free from harsh haram alcohols such as ethanol and denatured alcohol and do not contain any animal derived ingredients.

ACTIVE INGREDIENTS

 The NO Grow range of hair removal products is based on the following formulation, modified for use on varying types of body hair from female facial hair, leg hair, underarm hair, etc to male body hair and thick coarse androgen-driven male beard hair: Aqua, Guar gum, Mercaptoacetic Acid, Propylene Glycol, White Oil, Vaseline, KOH, Stearyl Alcohol, Calcium Oxide, Lauryl Isoquinolinium Bromide Aloe Vera.

FDA APPROVAL

NO Grow is FDA approved on both accounts. In other words approved on the purpose of the products, as well as the active ingredients. In order to be FDA approved on the PURPOSE of the product, NO Grow submitted case studies based on a period of 9 years, consisting of the following clients:

  • Male
  • Female
  • Pregnant Ladies
  • Transgender
  • Change Of Life
  • Chemotherapy Patients

NO Grow is also FDA approved on the ACTIVE INGREDIENTS of the products due to it being:

  • Halal
  • Vegan
  • Vegetarian
  • No Animal Derived Ingredients
  • No Human Derived Ingredients

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